Current Lab Members

Dr. Heer Mehta

Dr. Heer Mehta

Research scientist

Email: heer.mehta@rice.edu

Heer works as a microbiologist in the Shamoo Lab and studies mechanisms leading to antimicrobial resistance in clinically relevant pathogens such as Pseudomonas aeruginosa, Nocardia and the bioterrorism agent Francisella tularensis. Her PhD work at UTDallas involved studying the response of uropathogenic E. coli to nitric oxide. She enjoys mentoring undergraduate and graduate students and in her free time, likes cooking, baking, running and crocheting.

https://anchor.fm/bioinfopod/episodes/Dr--Heer-Mehta-Antibiotic-Resistance-and-Experimental-Evolution-ep8bqf

Twitter @heer_mehta

Dr. Seokju Seo

Dr. Seokju Seo

Postdoctoral research associate

Email: ss210@rice.edu

Seokju Seo is a postdoctoral research associate in the Shamoo lab. He holds his Ph.D. from Florida Atlantic University, Boca Raton. His current research is the development of a novel microfluidic platform for biomarker discovery. Changes in pathogen genetic variation will be identified through the adaptation/selection of multidrug-resistant pathogens encapsulated in microemulsions. His Ph.D. researches include microbubbles and droplets-based microfluidics approach to studies of carbon capture and sequestration (CCS) and enhanced oil recovery (EOR). Gas-water-oil interactions between the interfaces under CCS and EOR reservoirs-specific conditions were studied using bubbles/droplets dynamics in the microchannel. Google Scholar profile: https://scholar.google.com/citations?user=8uAsBC8AAAAJ&hl=en

Dr. Yizhe Zhang

Dr. Yizhe Zhang

Postdoctoral research associate

Email: yz174@rice.edu

Yizhe is a postdoc researcher in the Shamoo lab, and mainly interested in studying the interactions between bacteria and mammalian cells at the single-cell level through the combination of microfluidics and single-cell biochemical techniques. Yizhe obtained her PhD in Chemical Physics from Harvard University, studying drop-based microfluidics and its applications in biology. Prior to joining the Shamoo lab, Yizhe worked on developing single-cell tools for measuring proteoforms in single mammalian cells at U.C.Berkeley.

Ramya Ganiga Prabhakar

Ramya Ganiga Prabhakar

Graduate student

Email: rg42@rice.edu

Ramya Ganiga Prabhakar is a graduate student in the Biochemistry and Cell Biology (BCB) program at Rice University. In the Shamoo lab, Ramya is developing a novel platform to study single cell bacterial evolution using approaches from Synthetic biology and Microfluidics. Ramya is passionate about leadership and is currently the Secretary of BCB Graduate Student Association (GSA) and a board member of Rice Wiki Women, a student led club for women in STEM. Outside of work, Ramya enjoys star gazing, painting, baking, watching Sci-fi movies and reading.

Yue Zhou

Yue Zhou

Graduate student

Email: yue.zhou@rice.edu

Yue is working on understanding the biochemical and molecular basis of daptomycin resistance in Enterococcus faecium. Daptomycin is a cyclic lipopeptide antibiotic that is currently used to treat vancomycin-resistant enterococci infections. Resistance to this drug has emerged after its extended use in the clinic, and thus it is important to restore its efficacy. Yue is seeking to elucidate the mechanism behind daptomycin resistance and identify potential targets for inhibitors, thus delaying the evolution process. A number of candidates involved in acquiring resistance have been identified by previous lab members. She will combine structural and biochemical studies to understand the characteristics of those targets and explain how they confer daptomycin resistance in enterococci.

Xinhao Song

Xinhao Song

Graduate student

Email: xinhao.SONG@rice.edu

Xinhao is a PhD student in the Shamoo lab. He obtained my BSc degree from Nankai University in China and joined the Shamoo group in 2017. He is interested in topics related to human health, especially the development of novel drugs and therapies. His current project focuses on the experimental evolution of social interactions among genus Streptomyces and the identification of the secondary metabolite molecules mediating such interactions.

Adeline Supandy

Adeline Supandy

Graduate student

Email: Adeline.Supandy@rice.edu

Adeline is a graduate student in the Shamoo lab. Her current project focuses on identifying mechanisms of daptomycin resistance in Enterococcus faecium.

David Ibarra

David Ibarra

Graduate student

Email: di3@rice.edu

David is a PhD student in the Shamoo lab. He obtained a Biochemistry and Genetics degree from Texas A&M University. His current project focuses on the use of experimental evolution alongside a novel microfluidic platform to discover new antimicrobial molecules. In his spare time, he likes to read, play video games, and watch movies.

John Shin

John Shin

Undergraduate student

Email: john.shin@rice.edu

I am a sophomore studying Biochemistry and Cell Biology. My hobbies are playing my cello and binge watching shows!

Saoirse Disney-McKeethen

Saoirse Disney-McKeethen

Undergraduate student

Email: hsd2@rice.edu

Saoirse is a freshman at Baker College, studying Biochemistry and Cell Biology. She is originally from Fayetteville, AR, and in her free time she enjoys knitting, crocheting, and beadwork.

Sarah Kong

Sarah Kong

Undergraduate student

Email: hsd2@rice.edu

Sarah is a sophomore studying Biochemistry and Cell Biology originally from the Woodlands, TX. She is working on an undergraduate project mentored by Xinhao Song to learn more about the experimental evolution of social interactions among genus Streptomyces.