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Ganiga Prabhakar R, Fan G, Alnahhas RN, Hirning AJ, Bennett MR, Shamoo Y. 2023. Indirect Enrichment of Desirable, but Less Fit Phenotypes, from a Synthetic Microbial Community Using Microdroplet Confinement. ACS Synth Biol.
Mehta HH, Song X, Shamoo Y. 2023. Intracellular Experimental Evolution of Francisella tularensis Subsp. holarctica Live Vaccine Strain (LVS) to Antimicrobial Resistance. ACS Infectious Disease. 9(2): 308–321.
Zhou Y, Utama B, Pratap S, Supandy A, Song X, Tran TT, Mehta HH, Arias CA, Shamoo Y. 2023. Enolpyruvate transferase MurAAA149E, identified during adaptation of Enterococcus faecium to daptomycin, increases stability of MurAA-MurG interaction. J Biol Chem. 299(3)
Mehta HH, Ibarra D, Marx CJ, Miller CR, Shamoo Y. 2022. Mutational Switch-Backs Can Accelerate Evolution of Francisella to a Combination of Ciprofloxacin and Doxycycline. Front Microbiol. 13: 904822.
Supandy A, Mehta HH, Tran TT, Miller WR, Zhang R, Xu L, Arias CA, Shamoo Y. 2022. Evolution of Enterococcus faecium in Response to a Combination of Daptomycin and Fosfomycin Reveals Distinct and Diverse Adaptive Strategies. Antimicrob Agents Chemother. 66(6)
Seo S, Prabhakar RG, Disney-McKeethen S, Song X, Mehta HH, Shamoo Y. 2022. Identification of Evolutionary Trajectories Associated with Antimicrobial Resistance Using Microfluidics. ACS Infect Dis. 8(1): 242-254.
Bazurto JV, Nayak DD, Ticak T, Davlieva M, Lee JA, Hellenbrand CN, Lambert LB, Benski OJ, Quates CJ, Johnson JL, Patel JS, Ytreberg FM, Shamoo Y, Marx CJ. 2021. EfgA is a conserved formaldehyde sensor that leads to bacterial growth arrest in response to elevated formaldehyde. PLoS Biol. 19(5).
Prater A. G., Mehta H. H., Beabout K., Supandy A., Miller W. R., Tran T. T., Arias C. A., & Shamoo Y.2021. Daptomycin resistance in Enterococcus faecium can be delayed by disruption of the LiaFSR stress response pathway. Antimicrob Agents Chemother. 65(4).
Mehta HH, Shamoo Y. 2020. Pathogenic Nocardia: A diverse genus of emerging pathogens or just poorly recognized? PLoS Pathog. 16(3).
Khan A, Davlieva M, Panesso D, Rincon S, Miller WR, Diaz L, Reyes J, Cruz MR, Pemberton O, Nguyen AH, Siegel SD, Planet PJ, Narechania A, Latorre M, Rios R, Singh KV, Ton-That H, Garsin DA, Tran TT, Shamoo Y, Arias CA. 2019. Antimicrobial sensing coupled with cell membrane remodeling mediates antibiotic resistance and virulence in Enterococcus faecalis. Proc Natl Acad Sci U S A. 116(52): 26925-32.
Prater AG, Mehta HH, Kosgei AJ, Miller WR, Tran TT, Arias CA, Shamoo Y. 2019. Environment Shapes the Accessible Daptomycin Resistance Mechanisms in Enterococcus faecium. Antimicrob Agents Chemother. 63(10).
Mehta H.H., Prater A.G., Beabout K., Elworth R.A.L., Karavis M., Gibbons H.S. and Shamoo Y. 2019. The Essential Role of Hypermutation in Rapid Adaptation to Antibiotic Stress. Antimicrob Agents Chemother. 63(7).
Rincon S., Panesso D., Miller W.R., Singh K.V., Cruz M.R., Khan A., Dinh A.Q., Diaz L., Rios R., Shamoo Y., Reyes J., Tran T.T., Garsin D.A. and Arias C.A. 2019. Disrupting Membrane Adaptation Restores In Vivo Efficacy of Antibiotics Against Multidrug-Resistant Enterococci and Potentiates Killing by Human Neutrophils. J Infect Dis. 220(3): 494-504
Miller W.R., Tran T.T., Diaz L., Rios R., Khan A., Reyes J., Prater A.G., Panesso D., Shamoo Y. and Arias C.A. 2019. LiaR-independent pathways to daptomycin resistance in Enterococcus faecalis reveal a multilayer defense against cell envelope antibiotics. Mol Microbiol. 111(3): 811-24.
Mehta H, Weng J, Prater A, Elworth RAL, Han X, Shamoo Y. 2018. Pathogenic Nocardia cyriacigeorgica and Nocardia nova Evolve To Resist Trimethoprim-Sulfamethoxazole by both Expected and Unexpected Pathways. Antimicrob Agents Chemother. 62(7).
Mehta H.H., Prater A.G. and Shamoo Y. 2018. Using experimental evolution to identify druggable targets that could inhibit the evolution of antimicrobial resistance. J Antibiot (Tokyo). 71(2): 279-86.
Davlieva M., Wu C., Zhou Y., Arias C.A. and Shamoo Y. 2018. Two Mutations Commonly Associated with Daptomycin Resistance in Enterococcus faecium LiaS(T120A) and LiaR(W73C) Appear To Function Epistatically in LiaFSR Signaling. Biochemistry. 57(49): 6797-805.
Perez AM, Gomez MM, Kalvapalle P, O'Brien-Gilbert E, Bennett MR, Shamoo Y. 2017. Using cellular fitness to map the structure and function of a major facilitator superfamily effluxer. Mol Syst Biol. 13(12): 964
Wang X., Davlieva M., Reyes J., Panesso D., Arias C.A. and Shamoo Y. 2017. A Novel Phosphodiesterase of the GdpP Family Modulates Cyclic di-AMP Levels in Response to Cell Membrane Stress in Daptomycin-Resistant Enterococci. Antimicrob Agents Chemother. 61(3).
Montealegre M.C., Roh J.H., Rae M., Davlieva M.G., Singh K.V., Shamoo Y. and Murray B.E. 2017. Differential Penicillin-Binding Protein 5 (PBP5) Levels in the Enterococcus faecium Clades with Different Levels of Ampicillin Resistance. Antimicrob Agents Chemother. 61(1).
Beabout K., McCurry M.D., Mehta H., Shah A.A., Pulukuri K.K., Rigol S., Wang Y., Nicolaou K.C. and Shamoo Y. 2017. Experimental Evolution of Diverse Strains as a Method for the Determination of Biochemical Mechanisms of Action for Novel Pyrrolizidinone Antibiotics. ACS Infect Dis. 3(11): 854-65.
Davlieva M., Tovar-Yanez A., DeBruler K., Leonard P.G., Zianni M.R., Arias C.A. and Shamoo Y. 2016. An Adaptive Mutation in Enterococcus faecium LiaR Associated with Antimicrobial Peptide Resistance Mimics Phosphorylation and Stabilizes LiaR in an Activated State. J Mol Biol. 428(22): 4503-19.
Beabout K., Hammerstrom T.G., Perez A.M., Magalhaes B.F., Prater A.G., Clements T.P., Arias C.A., Saxer G. and Shamoo Y. 2015. The ribosomal S10 protein is a general target for decreased tigecycline susceptibility. Antimicrob Agents Chemother. 59(9): 5561-6.